Leporinus multimaculatus can be diagnosed from all other species of anostomids except Hypomasticus julii, H. megalepis, H. pachycheilus, Leporinus gomesi, L. granti, L. nijsseni, L. santosi and L. torrenticola, by possessing one dark blotch lon midline of anterior portion of the flank (between opercle and origin of pelvic fin) surrounded by five to seven dark blotches (vs. anterior portion of flank with dark longitudinal stripes, or with dark transversal bars, or with dark blotches not forming the aforementioned pattern). Leporinus multimaculatus differs from Hypomasticus julii, H. pachycheilus, Leporinus gomesi, L. granti, L. nijsseni, and L. santosi, by having three teeth on premaxilla (vs. four), and subinferior mouth (vs. inferior in Hypomasticus julii and H. pachycheilus, and terminal in Leporinus gomesi, L. granti, L. nijsseni, and L. santosi); and from H. megalepis and L. torrenticola by possessing 12 scale rows around caudal peduncle (vs. 16) (Ref. 117595).

Description: Dorsal-fin rays ii,10; anal-fin rays ii,8; pectoral-fin rays i,14-17; pelvic-fin rays i,8 (Ref. 117595)